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1

Hen Egg White Lysozyme Expressed in, and Secreted from, Aspergillus niger is Correctly Processed and Folded

Archer, David B., Jeenes, David J., MacKenzie, Donald A., Brightwell, Gale, Lambert, Nigel, Lowe, Gordon, Radford, Sheena E., Dobson, Christopher M.

Journal:

Year:

1990

File:

PDF, 842 KB

1990

2

Weighing the evidence for structure: electrospray ionization mass spectrometry of proteins

Carol V Robinson, Sheena E Radford

Journal:

Year:

1995

Language:

english

File:

PDF, 559 KB

english, 1995

3

Fibril Growth Kinetics Reveal a Region of β2-microglobulin Important for Nucleation and Elongation of Aggregation

Geoffrey W. Platt, Katy E. Routledge, Steve W. Homans, Sheena E. Radford

Journal:

Journal of Molecular Biology

Year:

2008

Language:

english

File:

PDF, 1.12 MB

english, 2008

4

A Generic Mechanism of β2-Microglobulin Amyloid Assembly at Neutral pH Involving a Specific Proline Switch

Timo Eichner, Sheena E. Radford

Journal:

Journal of Molecular Biology

Year:

2009

Language:

english

File:

PDF, 1.87 MB

english, 2009

5

Systematic Examination of Polymorphism in Amyloid Fibrils by Molecular-Dynamics Simulation

Berryman, Joshua T., Radford, Sheena E., Harris, Sarah A.

Journal:

Biophysical Journal

Year:

2011

Language:

english

File:

PDF, 1020 KB

english, 2011

6

Energy landscapes of functional proteins are inherently risky

Gershenson, Anne, Gierasch, Lila M, Pastore, Annalisa, Radford, Sheena E

Journal:

Nature Chemical Biology

Year:

2014

Language:

english

File:

PDF, 2.71 MB

english, 2014

7

How TriC Folds Tricky Proteins

Zhuravleva, Anastasia, Radford, Sheena E.

Journal:

Year:

2014

Language:

english

File:

PDF, 419 KB

english, 2014

8

Mechanisms of amyloid formation revealed by solution NMR

Karamanos, Theodoros K., Kalverda, Arnout P., Thompson, Gary S., Radford, Sheena E.

Journal:

Progress in Nuclear Magnetic Resonance Spectroscopy

Year:

2015

Language:

english

File:

PDF, 10.26 MB

english, 2015

9

Amyloid Under the Atomic Force Microscope

Gosal, Walraj, Myers, Sarah, Radford, Sheena, Thomson, Neil

Journal:

Protein & Peptide Letters

Year:

2006

Language:

english

File:

PDF, 225 KB

english, 2006

10

Inducing protein aggregation by extensional flow

Dobson, John, Kumar, Amit, Willis, Leon F., Tuma, Roman, Higazi, Daniel R., Turner, Richard, Lowe, David C., Ashcroft, Alison E., Radford, Sheena E., Kapur, Nikil, Brockwell, David J.

Journal:

Proceedings of the National Academy of Sciences

Year:

2017

Language:

english

File:

PDF, 1.06 MB

english, 2017

11

Investigating the Structural Compaction of Biomolecules Upon Transition to the Gas-Phase Using ESI-TWIMS-MS

Devine, Paul W. A., Fisher, Henry C., Calabrese, Antonio N., Whelan, Fiona, Higazi, Daniel R., Potts, Jennifer R., Lowe, David C., Radford, Sheena E., Ashcroft, Alison E.

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2017

Language:

english

File:

PDF, 1.87 MB

english, 2017

12

Dynamic action of the Sec machinery during initiation, protein translocation and termination

Fessl, Tomas, Watkins, Daniel, Oatley, Peter, Allen, William John, Corey, Robin Adam, Horne, Jim, Baldwin, Steve A, Radford, Sheena E, Collinson, Ian, Tuma, Roman

Journal:

Year:

2018

Language:

english

File:

PDF, 2.74 MB

english, 2018

13

A new era for understanding amyloid structures and disease

Iadanza, Matthew G., Jackson, Matthew P., Hewitt, Eric W., Ranson, Neil A., Radford, Sheena E.

Journal:

Nature Reviews Molecular Cell Biology

Year:

2018

Language:

english

File:

PDF, 7.91 MB

english, 2018

14

Accurate Use of Single Molecule Fluorescence Correlation Spectroscopy to Determine Molecular Diffusion Times

Chris Gell, David J. Brockwell, Godfrey S. Beddard, Sheena E. Radford, Arnout P. Kalverda, D. Alastair Smith

Journal:

Single Molecules

Year:

2001

Language:

english

File:

PDF, 81 KB

english, 2001

15

Probing Dynamics within Amyloid Fibrils Using a Novel Capping Method

Geoffrey W. Platt, Wei-Feng Xue, Steve W. Homans, Sheena E. Radford

Journal:

Angewandte Chemie

Year:

2009

Language:

english

File:

PDF, 369 KB

english, 2009

16

Probing Dynamics within Amyloid Fibrils Using a Novel Capping Method

Geoffrey W. Platt, Wei-Feng Xue, Steve W. Homans, Sheena E. Radford

Journal:

Angewandte Chemie International Edition

Year:

2009

Language:

english

File:

PDF, 369 KB

english, 2009

17

Phosphorylation as a Tool To Modulate Aggregation Propensity and To Predict Fibril Architecture

Dr. Nathalie M. Valette, Prof. Sheena E. Radford, Dr. Sarah A. Harris, Dr. Stuart L. Warriner

Journal:

Year:

2012

Language:

english

File:

PDF, 6.21 MB

english, 2012

18

Towards an understanding of the structural molecular mechanism of β2-microglobulin amyloid formation in vitro

Sheena E. Radford, Walraj S. Gosal, Geoffrey W. Platt

Journal:

Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics

Year:

2005

Language:

english

File:

PDF, 725 KB

english, 2005

19

HDX-ESI-MS reveals enhanced conformational dynamics of the amyloidogenic proteinβ2-microglobulin upon release from the MHC-1

John P. Hodkinson, Thomas R. Jahn, Sheena E. Radford, Alison E. Ashcroft

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2009

Language:

english

File:

PDF, 1.00 MB

english, 2009

20

Force mode atomic force microscopy as a tool for protein folding studies

Robert B. Best, David J. Brockwell, José L. Toca-Herrera, Anthony W. Blake, D.Alastair Smith, Sheena E. Radford, Jane Clarke

Journal:

Analytica Chimica Acta

Year:

2003

Language:

english

File:

PDF, 507 KB

english, 2003

21

Significant hydrogen exchange protection in GroEL-bound DHFR is maintained during iterative rounds of substrate cycling

Michael Groß, Carol V. Robinson, Mark Mayhew, F. Ulrich Hartl, Sheena E. Radford

Journal:

Protein Science

Year:

1996

Language:

english

File:

PDF, 2.32 MB

english, 1996

22

Comparison of the transition state ensembles for folding of Im7 and Im9 determined using all-atom molecular dynamics simulations with ϕ value restraints

Emanuele Paci, Claire T. Friel, Kresten Lindorff-Larsen, Sheena E. Radford, Martin Karplus, Michele Vendruscolo

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

2004

Language:

english

File:

PDF, 919 KB

english, 2004

23

Hydrogen exchange in native and denatured states of hen egg-white lysozyme

Sheena E. Radford, Matthias Buck, Karen D. Topping, Christopher M. Dobson, Philip A. Evans

Journal:

Proteins: Structure, Function, and Bioinformatics

Year:

1992

Language:

english

File:

PDF, 1.03 MB

english, 1992

24

Separation of β2-microglobulin conformers by high-field asymmetric waveform ion mobility spectrometry (FAIMS) coupled to electrospray ionisation mass spectrometry

Antoni J. H. Borysik, Paul Read, David R. Little, Robert H. Bateman, Sheena E. Radford, Alison E. Ashcroft

Journal:

Rapid Communications in Mass Spectrometry

Year:

2004

Language:

english

File:

PDF, 362 KB

english, 2004

25

Investigating the structural properties of amyloid-like fibrils formed in vitro from β2-microglobulin using limited proteolysis and electrospray ionisation mass spectrometry

Sarah L. Myers, Neil H. Thomson, Sheena E. Radford, Alison E. Ashcroft

Journal:

Rapid Communications in Mass Spectrometry

Year:

2006

Language:

english

File:

PDF, 345 KB

english, 2006

26

Production of15N-labelled hen egg white lysozyme usingAspergillus niger

Ian N. Roberts, Donald A. MacKenzie, David J. Jeenes, David B. Archer, Sheena E. Radford, Carol V. Robinson, Robin T. Aplin, Christopher M. Dobson

Journal:

Biotechnology Letters

Year:

1992

Language:

english

File:

PDF, 344 KB

english, 1992

27

Second Order Rate Constants of Donor-Strand Exchange Reveal Individual Amino Acid Residues Important in Determining the Subunit Specificity of Pilus Biogenesis

Aneika C. Leney, Gilles Phan, William Allen, Denis Verger, Gabriel Waksman, Sheena E. Radford, Alison E. Ashcroft

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2011

Language:

english

File:

PDF, 628 KB

english, 2011

28

Monitoring Copopulated Conformational States During Protein Folding Events Using Electrospray Ionization-Ion Mobility Spectrometry-Mass Spectrometry

David P. Smith, Kevin Giles, Robert H. Bateman, Sheena E. Radford, Alison E. Ashcroft

Journal:

Journal of the American Society for Mass Spectrometry

Year:

2007

Language:

english

File:

PDF, 705 KB

english, 2007

29

The Yin and Yang of protein folding

Thomas R. Jahn, Sheena E. Radford

Journal:

Year:

2005

Language:

english

File:

PDF, 253 KB

english, 2005

30

Understanding the complex mechanisms of β2-microglobulin amyloid assembly

Timo Eichner, Sheena E. Radford

Journal:

Year:

2011

Language:

english

File:

PDF, 684 KB

english, 2011

31

10.1038/10735

Radford, Sheena E., Coyle, Joseph E., Texter, Frieda L., Ashcroft, Alison E., Masselos, Dimitris, Robinson, Carol V.

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 1018 KB

english, 1999

32

Demonstration by NMR of folding domains in lysozyme

Miranker, Andrew, Radford, Sheena E., Karplus, Martin, Dobson, Christopher M.

Journal:

Year:

1991

File:

PDF, 637 KB

1991

33

The folding of hen lysozyme involves partially structured intermediates and multiple pathways

Radford, Sheena E., Dobson, Christopher M., Evans, Philip A.

Journal:

Year:

1992

File:

PDF, 664 KB

1992

34

Conformation of GroEL-bound α-lactalbumin probed by mass spectrometry

Robinson, Carol V., Groß, Michael, Eyles, Stephen J., Ewbank, Jonathan J., Mayhew, Mark, Hartl, F. Ulrich, Dobson, Christopher M., Radford, Sheena E.

Journal:

Year:

1994

File:

PDF, 805 KB

1994

35

Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis

Booth, David R., Sunde, Margaret, Bellotti, Vittorio, Robinson, Carol V., Hutchinson, Winston L., Fraser, Paul E., Hawkins, Philip N., Dobson, Christopher M., Radford, Sheena E., Blake, Colin C. F.

Journal:

Year:

1997

File:

PDF, 1.53 MB

1997

36

10.1038/6683

Kleanthous, Colin, Hemmings, Andrew M., Kühlmann, Ulrike C., Pommer, Ansgar J., Ferguson, Neil, Radford, Sheena E., Moore, Geoffrey R., James, Richard

Journal:

Natural Structural Biology

Year:

1999

Language:

english

File:

PDF, 874 KB

english, 1999

37

10.1038/83074

Roder, Heinrich, Radford, Sheena E., Capaldi, Andrew P., Shastry, M. C. Ramachandra, Kleanthous, Colin

Journal:

Natural Structural Biology

Year:

2001

Language:

english

File:

PDF, 1.26 MB

english, 2001

38

Co-translocational misfolding in the ER of living cells

Radford, Sheena E.

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 152 KB

english, 2003

39

Pseudospecific docking surfaces on electron transfer proteins as illustrated by pseudoazurin, cytochrome c550 and cytochrome cd1 nitrite reductase

Williams, Pamela A., Fülöp, Vilmos, Leung, Yun-Chung, Chan, Christopher, Moir, James W. B., Howlett, Geoffrey, Ferguson, Stuart J., Radford, Sheena E., Hajdu, Janos

Journal:

Natural Structural Biology

Year:

1995

File:

PDF, 1.10 MB

1995

40

Im7 folding mechanism: misfolding on a path to the native state

Capaldi, Andrew P., Kleanthous, Colin, Radford, Sheena E.

Journal:

Natural Structural Biology

Year:

2002

Language:

english

File:

PDF, 2.45 MB

english, 2002

41

Structural properties of an amyloid precursor of β2-microglobulin

McParland, Victoria J., Kalverda, Arnout P., Homans, Steve W., Radford, Sheena E.

Journal:

Natural Structural Biology

Year:

2002

Language:

english

File:

PDF, 1.84 MB

english, 2002

42

Pulling geometry defines the mechanical resistance of a β-sheet protein

Brockwell, David J, Paci, Emanuele, Zinober, Rebecca C, Beddard, Godfrey S, Olmsted, Peter D, Smith, D Alastair, Perham, Richard N, Radford, Sheena E

Journal:

Natural Structural Biology

Year:

2003

Language:

english

File:

PDF, 1.01 MB

english, 2003

43

The mechanism of folding of Im7 reveals competition between functional and kinetic evolutionary constraints

Friel, Claire T, Alastair Smith, D, Vendruscolo, Michele, Gsponer, Joerg, Radford, Sheena E

Journal:

Nature Structural and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 845 KB

english, 2009

44

An expanding arsenal of experimental methods yields an explosion of insights into protein folding mechanisms

Bartlett, Alice I, Radford, Sheena E

Journal:

Nature Structural and Molecular Biology

Year:

2009

Language:

english

File:

PDF, 558 KB

english, 2009

45

Amyloid formation under physiological conditions proceeds via a native-like folding intermediate

Jahn, Thomas R, Parker, Martin J, Homans, Steve W, Radford, Sheena E

Journal:

Nature Structural and Molecular Biology

Year:

2006

Language:

english

File:

PDF, 463 KB

english, 2006

46

β Edge strands in protein structure prediction and aggregation

Jennifer A. Siepen, Sheena E. Radford, David R. Westhead

Journal:

Protein Science

Year:

2003

Language:

english

File:

PDF, 265 KB

english, 2003

47

Role of the single disulphide bond of β2-microglobulin in amyloidosis in vitro

David P. Smith, Sheena E. Radford

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 204 KB

english, 2001

48

A partially folded intermediate species of the β-sheet protein apo-pseudoazurin is trapped during proline-limited folding

John S. Reader, Nico A. J. Van Nuland, Gary S. Thompson, Stuart J. Ferguson, Christopher M. Dobson, Sheena E. Radford

Journal:

Protein Science

Year:

2001

Language:

english

File:

PDF, 412 KB

english, 2001

49

A near-native state on the slow refolding pathway of hen lysozyme

Sunita K. Kulkarni, Alison E. Ashcroft, Sheena E. Radford, Michael Carey, Dimitris Masselos, Carol V. Robinson

Journal:

Protein Science

Year:

1999

Language:

english

File:

PDF, 665 KB

english, 1999

50

The structure and dynamics in solution of Cu(I) pseudoazurin from Paracoccus pantotrophus

Gary S. Thompson, Sheena E. Radford, Yun-Chung Leung, Christina Redfield, Stuart J. Ferguson

Journal:

Protein Science

Year:

2000

Language:

english

File:

PDF, 2.05 MB

english, 2000